Transcriptome Analysis of Neisseria meningitidis during Infection

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Transcriptome analysis of Neisseria meningitidis during infection.

Neisseria meningitidis is the cause of septicemia and meningococcal meningitis. During the course of infection, N. meningitidis encounters multiple environments within its host, which makes rapid adaptation to environmental changes a crucial factor for neisserial pathogenicity. Employing oligonucleotide-based DNA microarrays, we analyzed the transcriptome of N. meningitidis during two key steps...

متن کامل

Global Transcriptome Analysis Reveals Small RNAs Affecting Neisseria meningitidis Bacteremia

Most bacterial small RNAs (sRNAs) are post-transcriptional regulators involved in adaptive responses, controlling gene expression by modulating translation or stability of their target mRNAs often in concert with the RNA chaperone Hfq. Neisseria meningitides, the leading cause of bacterial meningitis, is able to adapt to different host niches during human infection. However, only a few sRNAs an...

متن کامل

Analysis of the regulated transcriptome of Neisseria meningitidis in human blood using a tiling array.

Neisseria meningitidis is the major cause of septicemia and meningococcal meningitis. During the course of infection, the bacterium must adapt to different host environments as a crucial factor for survival and dissemination; in particular, one of the crucial factors in N. meningitidis pathogenesis is the ability to grow and survive in human blood. We recently showed that N. meningitidis alters...

متن کامل

In silico Analysis and Modeling of ACP-MIP–PilQ Chimeric Antigen from Neisseria meningitidis Serogroup B

Background: Neisseria meningitidis, a life-threatening human pathogen with the potential to cause large epidemics, can be isolated from the nasopharynx of 5–15% of adults. The aim of the current study was to evaluate biophysical and biochemical properties and immunological aspects of chimeric acyl-carrier protein-macrophage infectivity potentiator protein-type IV pilus biogenesis protein ...

متن کامل

Extrameningeal complications of Neisseria meningitidis serogroup W135 infection.

Received 3 March 2004; accepted 4 March 2004; electronically published 12 May 2004. Reprints or correspondence: Dr. Michael A. Apicella, Dept. of Microbiology, University of Iowa, 51 Newton Rd., Iowa City, IA 52242 ([email protected]). Clinical Infectious Diseases 2004; 38:1638–9 2004 by the Infectious Diseases Society of America. All rights reserved. 1058-4838/2004/3811-0023$15.00 Nei...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 2003

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.185.1.155-164.2003